Javier Montenegro


Research Interests

Javier Montenegro received his master degree (2003) and PhD (2009) from the University of Santiago de Compostela, under the direction of Prof. Susana López, working in the field of synthetic retinoids. In 2005 he was a visiting scientist in the group of Prof. Steven Ley at Cambridge University (Total Synthesis). In 2007 he was a visiting scientist at the Scripps Research Institute (La Jolla) working with Prof. Reza M. Ghadiri in prebiotic chemistry and  supramolecular dynamic polymers. In 2009 he moved to the University of Geneva for postdoctoral studies with Prof. Stefan Matile in biosensing, synthetic transport systems and controlled delivery. In 2012 he returned to Spain as a Juan de la Cierva fellow to work at the CIQUS associated with Prof. Juan R. Granja. He obtained a Ramon y Cajal contract at the Organic Chemistry Department and the CIQUS in the University of Santiago de Compostela. He has received several of the most prestigious international awards including: a Starting Grant from the ERC (2015), a Young Investigator Grant of the Human Frontier Science Program (2017), JSP Fellow 52th Bürgenstock Conference (2017), the Prize of Young Investigators of the Spanish Royal Society of Chemistry (2018) and the Prize of Young Research Group Leaders in Chemical Biology of the RSEQ (2019).

Peptide/Cas9 Nanostructures for Ribonucleoprotein Cell Membrane Transport and Gene Edition” Lostalé-Seijo, I.; Louzao, I.; Juanes, M.; Montenegro, J. Chem. Sci., 2017, 8, 7883–8466.

“Supramolecular Functional Assemblies: Dynamic Membrane Transporters and Peptide Nanotubular Composites” Fuertes, A.; Juanes, M.; Granja. R. J.;  Montenegro, J. Chem. Commun., 2017, 53, 7861-7871.

In situ” Functionalized Polymers for siRNA Delivery”, Priegue, J. M.; Crisan, D. N.; Martínez-Costas, J;  Granja, J. R.; Fernandez-Trillo, F.; Montenegro, J. Angew. Chem. Int. Ed. 2016, 55, 7492-7495.

Self-assembly of Silver Metal Clusters of Small Atomicity on Cyclic Peptide               Nanotubes”, M. Cuerva, R. García-Fandiño, C. Vázquez-Vázquez, M. A. López-Quintela, Javier Montenegro*, Juan R. Granja, ACS Nano, 2015, 9, 10834-10843.

Cellular Uptake: Lessons from Supramolecular Organic Chemistry”, G. Gasparini, E.-K. Bang, J, Montenegro and S. Matile, Chem. Commun. 2015, 51, 10389-10402 .

Coupling of Peptides and Carbon Nanotubes” Montenegro, J.,* Vázquez-Vázquez, C., Kalinin, A., Geckeler, K. E., & Granja, J. R. Coupling of carbon and Peptide nanotubes. J. Am. Chem. Soc., 2014, 136, 2484–2491.

Ion Channel Models Based on Self-Assembling Cyclic Peptide Nanotubes.” Montenegro, J.; Ghadiri, M. R.; Granja, J. R. Acc. Chem. Res., 2013, 46, 2955–2965.

Dynamic Amphiphile Libraries To Screen for the “Fragrant” Delivery of siRNA into HeLa Cells and Human Primary Fibroblasts.” Gehin, C.; Montenegro, J.; Bang, E.-K.; Cajaraville, A.; Takayama, S.; Hirose, H.; Futaki, S.; Matile, S.; Riezman, H. J. Am. Chem. Soc., 2013, 135, 9295–9298.

Recent synthetic transport systems.” Matile, S.; Vargas Jentzsch, A.; Montenegro, J.; Fin, A.  Chem. Soc. Rev., 2011, 40, 2453–2474.

Experimental evidence for the functional relevance of anion-π interactions.” Dawson, R. E.; Hennig, A.; Weimann, D. P.; Emery, D.; Ravikumar, V.; Montenegro, J.; Takeuchi, T.; Gabutti, S.; Mayor, M.; Mareda, J.; Schalley, C. A.; Matile, S.  Nat. Chem., 2010, 2, 533–538.

Selected Publications

Javier Montenegro CVhttps://www.dropbox.com/s/my7755itsj3gh3b/CV_Javier_Montenegro.pdf?dl=0https://www.dropbox.com/s/my7755itsj3gh3b/CV_Javier_Montenegro.pdf?dl=0shapeimage_2_link_0