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Chemistry / Supramolecular / System / Biology

Publications

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67. "Boron Clusters as Broadband Membrane Carriers." Barba-Bon, A.; Salluce, G.; Lostalé-Seijo, I.; Assaf, K. I.; Hennig, A.; Montenegro, J.; Nau, W.  Nature, 2022, 603, 637–642.

66. "Self-Healing Cyclic Peptide Hydrogels" Bayon-Fernández, A.; Méndez-Ardoy, A.;  Álvarez-Lorenzo, C.; Granja, J.; Montenegro, J. J. Mat. Chem. B, 2023, 11, 606-617.

65. "A 3D Peptide/[60]Fullerene Hybrid for Multivalent Recognition" Gallego, I.; Ramos-Soriano, J.; Méndez-Ardoy, A.; Cabrera-González, J.; Lostalé-Seijo, I.; Illescas, B. M.; Reina, J. J.; Martín, N.; Montenegro, J. Angew. Chem. Int. Ed., 2022, 61, e202210043.

64. “Dynamic Nanosurface Reconfiguration by Host-Guest Supramolecular Intereactions" Fernádez-Caro, H.; ,Méndez-Ardoy, A.; Montenegro, J. Nanoscale, 2022,14, 3599-3608.

62. “Glycan Shields for Penetrating Peptides"  Gallego, I.; Montenegro, J. Chem. Commun. 2022, 58, 1394-1397.

63. “Bottom-Up Supramolecular Assembly in the Second Dimension"  Insua, I.; Bergueiro, J.; Méndez-Ardoy, A.; Lostalé-Seijo, I.; Montenegro, J. Chem. Sci. 2022, 13, 3057–3068.

61. "Cyclization and Self-Assembly of Cyclic Peptides". Méndez-Ardoy A.; Insua, I.; Granja, J.; Montenegro, J. Methods Mol Biol. 2022; 2371:449-466. doi: 10.1007/978-1-0716-1689-5_24. PMID: 34596863.

60. “1D alignment of proteins and other nanoparticles by using reversible covalent bonds on cyclic peptide nanotubes"   Priegue, J.M.; Louzao, I.; Gallego, I.; Montenegro, J. Granja, J. R.; Org. Chem. Front. 2022, 9, 1226-1233.


59. “Supramolecular fibrillation of peptide amphiphiles induces environmental responses in aqueous droplets" Booth, R.; Insua, I.; Ahmed, S.; Rioboo, A.; Montenegro, J.; Nature Communications 2021, 12, 6421.

58. “The Emergence of Order: A Closer Look at Peptide Assembly and Its Complexity" Mendez-Ardoy, A.; Bergueiro, J.; Montenegro, J.; Matter 2021, 10, 3081-3083.

57. “Short Oligoalanine Helical Peptides for Supramolecular Nanopore Assembly and Protein Cytosolic Delivery" Pazo, M.; Salluce, G.; Lostalé-Seijo, I.; Juanes, M., Gonzalez, F.; García-Fandiño, R.; Montenegro, J.; RSC Chemical Biology 2021, 2, 503-https://doi.org/10.1039/d0cb00103a512.

56. “An Adhesive Peptide From the C-Terminal Domain of α-Synuclein for Single-layer Adsorption of Nanoparticles on substrates" Bhak, G.; Méndez-Ardoy, A.; Escobedo, A.;  Salvatella, X.; Montenegro, J.; Bioconjugate Chemistry 2020, 12, 2759-2766.

55. “Stronger Together: Multivalent Phage Capsids Inhibit Virus Entry" Gallego, I.; Lostalé-Seijo, I.; Montenegro, J.; ChemBioChem 2021, 22, 478-480

54. “Sequence Decoding of 1D to 2D Self-Assembing Cyclic Peptides" Díaz, S.; Insua, I.; Bhak, G.; Montenegro, J.; Chem. Eur. J. 2020, 26, 14765-14770.

53. “Synthetic Supramolecular Systems in Life-like Materials and Protocell Models" Insua, I.; Montenegro, J.; Chem 2020, 6, 1652-1682.

52. “Spatially controlled supramolecular polymerization of peptide nanotubes by microfluidics Méndez-Ardoy, A.; Bayón-Fernández, A.; Yu, Z.; Abell, C.; Granja, J.R.; Montenegro, J.; Angew. Chem. Int. Ed. 2020, 59, 6902-6908.

51. “Synthesis and Supramolecular Functional Assemblies of Ratiometric pH Probes” Méndez-Ardoy, A.; Reina, J. J.; Montenegro, J.; Chem. Eur. J. 2020, 26, 7516-7536.

50. “1D to 2D Self Assembly of Cyclic Peptides” Insua, I.; Montenegro, J.; J. Am. Chem. Soc. 2020, 142, 300-307.

49. “Detection of Oligomeric Amyloid Aggregates in Real-Time Using Metal Complexes” Jiang, B.; Aliyan, A.; Cook, N. P.; Augustine, A.; Bhak, G.; Maldonado, R.; Smith McWilliams, A. D.; Flores, E.; Mendez, N. G.; Godoy, F.; Montenegro, J.; Moreno-Gonzalez, I.; Martí. A. A.; J. Am. Chem. Soc. 2019, 141, 15605-15610.

47. “Messenger RNA delivery by hydrazone-activated polymers” Juanes, M.; Creese, O.; Fernandez-Trillo, F.; Montenegro, J.; MedChemComm 2019, 10, 1138-1144.

* Contribution to the 2019 Special Issue on Young Talents in Medicinal Chemistry.

46. “Péptidos penetrantes celulares: descripción, mecanismo y aplicaciones” Gallego, I.; Rioboo, A.; Montenegro, J.; Anales de Química 2019, 115, 9-21.

* Front Cover and invitation as Prize of Young Researchers of RSEQ.

45. “Glycosylated Cell Penetrating Peptides, GCPPs” Gallego, I.; Rioboo, A.; Reina, J. J.; Díaz, B.; Canales, A.; Cañada, F. J.; Guerra-Varela, J.; Sánchez, L.; Montenegro, J.; ChemBioChem 2019, 20, 1400-1409.

* Contribution to the 2019 Special Issue on ChemBioTalents

44. “Self-Assembled Micro-Fibres by Oxime Connection of Linear Peptide Amphiphiles” Booth, R.; Insua, I.; Bhak, G.; Montenegro, J.; Org. Biomol. Chem. 2019, 17, 1984-1991.

* Contribution to the 2018 Special Issue on Organic & Biomolecular Chemistry New Talent Themed Issue


43. “Where in the cell is our cargo? Current methods to study intracellular cytosolic localization.” Méndez-Ardoy, A.; Lostalé-Seijo, I.; Montenegro, J.; ChemBioChem 2018, 20, 488-498.

* Contribution to the 2018 Special Issue on Biosensing and Bioimaging

42. “Synthetic materials at the forefront of gene delivery” Lostalé-Seijo, I.; Montenegro, J.; Nat. Rev. Chem. 2018, 2, 258-277.

41. “Oligoalanine Helical Callipers for Cell Penetration” Pazo, M.; Juanes, M.; Lostalé-Seijo, I.; Montenegro, J.; Chem. Commun. 2018, 54, 6919-6922.

40. “Supramolecular Recognition and Selective Protein Uptake by Peptide Hybrids” Juanes, M.; Lostalé-Seijo, I.; Granja, J.; Montenegro, J.; Chem. Eur. J. 2018, 24, 10689-10698.

39. “Different Length Hydrazone Activated Polymers for Plasmid DNA Condensation and Cellular Transfection” Priegue, J., Lostalé-Seijo, I., Crisan, D., Granja, J., Fernández-Trillo, F., Montenegro, J. Biomacromolecules, 2018, 19, 2638-2649.

38. “pH-Triggered Self-assembly and Hydrogelation of Cyclic Peptide Nanotubes Confined in Water Micro-droplets” Méndez-Ardoy, A., Granja, J. R., Montenegro, J. Nanoscale Horizons, 2018, 3, 391-396.

37. “Novel Supramolecular Nanoparticles Derived From Cucurbit[7]uril and Zwitterionic Surfactants” Fernández-Rosas, J., Pessêgo, M., Acuña, A., Vázquez-Vázquez, C., Montenegro, J. Parajó, M., Rodríguez-Dafonte, P., Nome, F., Garcia-Rio, L. Langmuir, 2018, 34, 3485-3493.

36. “Glycosyl Aldehydes, New Scaffolds for the Synthesis of Neo-Glycoconjugates via Bio-orthogonal Oxime Bond Formation” Reina, Jose J., Rioboo, A., Montenegro, J. Synthesis, 2018, 50, 831-845.

* 2017 Bürgenstock Special Section 2017: Future Stars in Organic Chemistry)

35. “Peptide/Cas9 Nano-structures for Ribonucleoprotein Cell Membrane Transport and Gene Edition” Lostalé-Seijo, I.; Louzao, I.; Juanes, M.; Montenegro, J. Chem. Sci., 2017, 8, 7923-7931.

34. “Highlights from the 52nd EUCHEM conference on stereochemistry, Bürgenstock, Switzerland, May 2017” Montenegro, J., Phipps, R. Chem. Commun. 2017, 53, 9960-9966.

* 2017 Invitation for conference report of the   Bürgenstock Conference 2017.

33. “Poly(acryloyl hydrazide), a versatile scaffold for the preparation of functional polymers: synthesis and post-polymerisation modification” Crisan, D. N,; Creese, O.;  Ball, R,; Brioso, J. L.,; Martyn, B.; Montenegro, J.; Fernandez-Trillo, F. Pol. Chem. 2017, 8, 4576-4584.

32. “Supramolecular Functional Assemblies: Dynamic Membrane Transporters and Peptide Nanotubular Composites” Fuertes, A.; Juanes, M.; Granja. R. J.;  Montenegro, J. Chem. Commun., 2017, 53, 7861-7871.

31. “Hydrazone-modulated peptides for efficient gene transfection” Louzao, I.; García-Fandiño, R.; Montenegro, J. J. Mat. Chem. B, 2017, 5, 4426-2234.

* Contribution to the 2017 Emerging Investigators Issue

30.  “Tuning the Properties of Penetrating Peptides by Oxime Conjugation” Pazo, M.; Fernández-Caro, H.; Priegue, J. M.; Lostalé, I.; Montenegro, J. Synlett, 2017, 28, 924-928.

*  Contribution to the Euchems Young Emerging Investigators

29. "Membrane-Disrupting Iridium (III) Oligocationic Organometallopeptides." Salvadó, I., Ilaria, G., Montenegro, J., Martínez-Costas, J., Brea, J. M., Loza, M. I., Vázquez-López, M., Vazquez, E. Chem. Commun. 2016, 52, 11008-110011.

28. “In situ” Functionalized Polymers for siRNA Delivery”, Priegue, J. M.; Crisan, D. N.; Martínez-Costas, J;  Granja, J. R.; Fernandez-Trillo, F.; Montenegro, J. Angew. Chem. Int. Ed. 2016, 55, 7492-7495.

27. “Self-assembly of Silver Metal Clusters of Small Atomicity on Cyclic Peptide               Nanotubes”, Cuerva, M.; García-Fandiño, R.; Vázquez-Vázquez, C.; López-Quintela, M. A. Montenegro*, J.; Granja, J. R. ACS Nano, 2015, 9, 10834-10843.

26. “Cellular Uptake: Lessons from Supramolecular Organic Chemistry”, Gasparini, G.; Bang, E.-K.; Montenegro, J.; Matile, S. Chem. Commun. 2015, 51, 10389-10402

25. “Membrane-Targeted Self-Assembling Cyclic Peptide Nanotubes” Rodríguez-Vázquez, N.; Ozores, H. L.; Guerra, A.; González-Freire, E.; Fuertes, A.; Panciera, M.; Priegue, J. M.; Outeiral, J.; Montenegro, J.; García-Fandiño, R.; Amorín, M. and Granja, J. R. Curr. Top. Med. Chem. 2015, 14, 2647-2661.

24. “Single-nucleotide-resolution DNA differentiation by pattern generation in lipid bilayer membranes” Priegue, J. M.; Montenegro,* J; Granja, J. R. Small, 2014, 10, 3613-3618.

23. “One-step chemoselective conversion of tetrahydropyranyl ethers to silyl-protected alcohols” Bergueiro, J., Montenegro, J.,* López, S., Saa, C. RSC Advances, 2014, 4, 14475-14479.

22. “Coupling of Peptides and Carbon Nanotubes” Montenegro, J.,* Vázquez-Vázquez, C., Kalinin, A., Geckeler, K. E., & Granja, J. R. J. Am. Chem. Soc., 2014, 136, 2484-2491.

21.“Ion Channel Models Based on Self-Assembling Cyclic Peptide Nanotubes.” Montenegro, J.; Ghadiri, M. R.; Granja, J. R. Acc. Chem. Res., 2013, 46, 2955-2965.


20. “Dynamic Amphiphile Libraries To Screen for the “Fragrant” Delivery of siRNA into HeLa Cells and Human Primary Fibroblasts.” Gehin, C.; Montenegro, J.; Bang, E.-K.; Cajaraville, A.; Takayama, S.; Hirose, H.; Futaki, S.; Matile, S.; Riezman, H. J. Am. Chem. Soc., 2013, 135, 9295-9298.

19. "Synthesis of 11-cis-retinoids by Hydrosilylation-Protodesilylation of an 11, 12-Didehydro Precursor: Easy Access to 11- and 12-Mono- and 11, 12-Dideuteroretinoids." Bergueiro, J.; Montenegro, J.; Saá, C.; López, S. Chem. Eur. J., 2012, 18, 14100-14107.

18. “Synthesis of an Enlarged Library of Dynamic DNA Activators with Oxime, Disulfide and Hydrazone Bridges.” Montenegro, J.; Bang, E.-K.; Sakai, N.; Matile, S. Chem. Eur. J., 2012, 18, 10436-10443.

17. “Cross-Coupling Reactions of Organosilicon Compounds in the Stereocontrolled Synthesis of Retinoids.” Bergueiro, J.; Montenegro, J.; Cambeiro, F.; Saá, C.; López, S. Chem. Eur. J., 2012, 18, 4401-4410.

16. “Total Synthesis of Millingtonine A” Wegner, J.; Ley, S. V.; Kirschning, A.; Hansen, A.-L.; Montenegro Garcia, J.; Baxendale, I. R. Org. Lett., 2012, 14, 696-699.

15. “Recent Progress with Functional Biosupramolecular Systems.” Doval, D. A.; Areephong, J.; Bang, E.-K.; Bertone, L.; Charbonnaz, P.; Fin, A.; Lin, N.-T.; Lista, M.; Matile, S.; Montenegro, J.; Orentas, E.; Sakai, N.; Tran, D.-H.; Jentzsch, A. V. Langmuir, 2011, 27, 9696-9705.

14. “Pattern generation with synthetic sensing systems in lipid bilayer membranes.” Takeuchi, T.; Montenegro, J.; Hennig, A.; Matile, S. Chem. Sci., 2011, 2, 303-307.

12. “Conceptually new entries into cells.” Montenegro, J.; Gehin, C.; Bang, E.-K.; Fin, A.; Doval, D. A.; Riezman, H.; Sakai, N.; Matile, S. Chimia, 2011, 65, 853-858.

13. “Synthetic polyion-counterion transport systems in polymersomes and gels.” Montenegro, J.; Braun, J.; Fischer-Onaca, O.; Meier, W.; Matile, S. Org. Biomol. Chem., 2011, 9, 6623-6628.

11. “Comprehensive screening of octopus amphiphiles as DNA activators in lipid bilayers: implications on transport, sensing and cellular uptake.” Montenegro, J.; Fin, A.; Matile, S. Org. Biomol. Chem., 2011, 9, 2641-2647.

10. “Recent synthetic transport systems.” Matile, S.; Vargas Jentzsch, A.; Montenegro, J.; Fin, A. Chem. Soc. Rev., 2011, 40, 2453-2474.

9. “Anionic Activators for Differential Sensing with Cell-Penetrating Peptides.” Montenegro, J.; Matile, S. Chem. Asian J., 2010, 6, 681-689.

8. “Dynamic Octopus Amphiphiles as Powerful Activators of DNA Transporters: Differential Fragrance Sensing and Beyond.” Montenegro, J.; Bonvin, P.; Takeuchi, T.; Matile, S. Chem. Eur. J., 2010, 16, 14159-14166.


7. “Experimental evidence for the functional relevance of anion-π interactions.” Dawson, R. E.; Hennig, A.; Weimann, D. P.; Emery, D.; Ravikumar, V.; Montenegro, J.; Takeuchi, T.; Gabutti, S.; Mayor, M.; Mareda, J.; Schalley, C. A.; Matile, S. Nat. Chem., 2010, 2, 533-538.

6. “Hiyama Cross-Coupling Reaction in the Stereospecific Synthesis of Retinoids.” Montenegro, J.; Bergueiro, J.; Saá, C.; López, S. Hiyama. Org. Lett., 2009, 11, 141-144.

5. "Counterion-Activated Translocation of Polyanions in Lipid Bilayers" Toshihide Takeuchi, Javier Montenegro, Stefan Matile. Chimia, 2009, 63, 469.

3. “Functional Biosupramolecular Systems.” Montenegro, J.; Hennig, A. Chimia, 2009, 63, 881-884.

4. “Dynamic polythioesters via ring-opening polymerization of 1,4-thiazine-2,5-diones.” Ura, Y.; Al-Sayah, M.; Montenegro, J.; Beierle, J. M.; Leman, L. J.; Ghadiri, M. R. Org. Biomol. Chem., 2009, 7, 2878-2884.

2. “Highly Convergent, Stereospecific Synthesis of 11- cis-Retinoids by Metal-Catalyzed Cross-Coupling Reactions of (Z)-1-Alkenylmetals.” López, S.; Montenegro, J.; Saá, C. J. Org. Chem., 2007, 72, 9572-9581.

1.“Synthesis of N-Heteroaryl Retinals and their Artificial Bacteriorhodopsins.” López, S.; Rodríguez, V.; Montenegro, J.; Saá, C.; Alvarez, R.; Silva López, C.; de Lera, A. R.; Simón, R.; Lazarova, T.; Padrós, E. ChemBioChem, 2005, 6, 2078-2087.

68. "Metallacarborane Cluster Anions of the COSAN-Type as Chaotropic Carriers for Transmembrane and Intracellular Delivery of Cationic Peptides" Chen Y., Barba-Bon, A., Grüner, B., Winterhalter, M., Aksoyoglu, M. A., Pangeni, S., Ashjari, M., Brix, K., Salluce, G., Folgar-Cameán, Y., Montenegro, J., Nau, W., W. J. Am. Chem. Soc., 2023, 145, 24, 13089–13098.

69. "Photoswitchable Calixarene Activators for Controlled Peptide Transport Across Lipid Membranes" Martins, J., Raimundo, B., Rioboo, A., Folgar-Cameán, Y., Montenegro, J., Basílio, N., J. Am. Chem. Soc., 2023, 145, 24, 13126–13133

70. "Self-Assembly of Cyclic Peptide Monolayers by Hydrophobic Supramolecular Hinges" Insua, I., Cardellini, A., Díaz, S, Bergueiro, J., Capelli, R., Pavan, G. M.,  Montenegro. J., Chem. Sci. 2023, In press